The B vitamins are a complex which consists of eight different vitamins: vitamin B1 (thiamine), vitamin B2 (riboflavin), vitamin B3 (niacin), vitamin B5 (pantothenic acid), vitamin B6 (pyridoxine), vitamin B7 (biotin), vitamin B9 (folate), and vitamin B12 (cobalamin). Thiamine is an essential vitamin which is important for the metabolism of glucose. High blood sugar levels and alcoholism lead to a drastically increased need for thiamine. Riboflavin, on the other hand, is an essential vitamin needed for different enzyme systems in the body to function properly. Riboflavin deficiency negatively affects the mucous membrane, particularly in the mouth and throat, and it can increase the risk of cardiovascular diseases. Another vitamin, Niacin, is an essential vitamin which positively affects both cholesterol and triglyceride levels. Niacin also raises nicotinamide adenine dinucleotide levels, a molecule that can be converted to ATP through a process called oxidative phosphorylation or cellular respiration in mitochondria. Pantothenic acid is an essential vitamin needed to form coenzyme A, an important molecule which is needed so that a lot of the enzymes in the body can function and that the human body produces energy. Vitamin B6, Pyridoxine, is needed to produce important coenzymes in the body. Folate is the natural form of folic acid; an essential vitamin is best known for its role in preventing neural tube defects in infants. Folate is also needed for the normal development of an infant's neural tube, as well as for producing cells and red blood cells in humans. Biotin is an essential vitamin needed for enzymatic functions in the body. It is also popular as a beauty supplement because it invigorates skin, hair, and nails. Vitamin B12, Cobalamin, is an essential vitamin which is important for the nerve system to function properly and for the development of red blood cells. The best B vitamins can be found in a complex from Innate Response which contains all eight B vitamins. B vitamins are water-soluble.